How to Pronounce “duloxetine”

American (US)

/duːˈlɑk.səˌtiːn/

noun — A drug that functions as an SNRI and is administered orally in the form of its hydrochloride C18H19NOS·HCl especially to treat depression, anxiety, and chronic pain (such as that associated with fibromyalgia and peripheral neuropathy). It is marketed under the trademark Cymbalta.

The final e is silent. The transcription /duːˈlɑk.səˌtiːn/ ends on a consonant sound, so the written e at the end of “duloxetine” is not pronounced.

Where the stress falls. “duloxetine” has 4 syllables, and the transcription /duːˈlɑk.səˌtiːn/ puts the primary stress mark (ˈ) before the second one — so the second syllable is the longest and loudest. The others are said quickly and lightly.

An unstressed vowel reduces to schwa. /duːˈlɑk.səˌtiːn/ contains a schwa /ə/ — the short, neutral “uh” that English unstressed syllables collapse into. Saying /ə/ there, instead of the vowel the spelling suggests, is most of what makes the word sound native.

What does "duloxetine" mean?

duloxetine (noun): A drug that functions as an SNRI and is administered orally in the form of its hydrochloride C18H19NOS·HCl especially to treat depression, anxiety, and chronic pain (such as that associated with fibromyalgia and peripheral neuropathy). It is marketed under the trademark Cymbalta.

What is the IPA transcription of "duloxetine"?

/duːˈlɑk.səˌtiːn/ in American English.

Which syllable is stressed in "duloxetine"?

“duloxetine” has 4 syllables, and the transcription /duːˈlɑk.səˌtiːn/ puts the primary stress mark (ˈ) before the second one — so the second syllable is the longest and loudest. The others are said quickly and lightly.